2017
Olaya, B.; Moneta, M. V.; Caballero, F. F.; Tyrovolas, S.; Bayes, I.; Ayuso-Mateos, J. L.; Haro, J. M.
Latent class analysis of multimorbidity patterns and associated outcomes in Spanish older adults: a prospective cohort study Artículo de revista
En: BMC Geriatr, vol. 17, no. 1, pp. 186, 2017.
Resumen | Enlaces | BibTeX | Etiquetas:
@article{pmid28821233,
title = {Latent class analysis of multimorbidity patterns and associated outcomes in Spanish older adults: a prospective cohort study},
author = {Olaya, B. and Moneta, M. V. and Caballero, F. F. and Tyrovolas, S. and Bayes, I. and Ayuso-Mateos, J. L. and Haro, J. M. },
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563011/},
year = {2017},
date = {2017-01-01},
journal = {BMC Geriatr},
volume = {17},
number = {1},
pages = {186},
abstract = {This study sought to identify multimorbidity patterns and determine the association between these latent classes with several outcomes, including health, functioning, disability, quality of life and use of services, at baseline and after 3 years of follow-up. We analyzed data from a representative Spanish cohort of 3541 non-institutionalized people aged 50 years old and over. Measures were taken at baseline and after 3 years of follow-up. Latent Class Analysis (LCA) was conducted using eleven common chronic conditions. Generalized linear models were conducted to determine the adjusted association of multimorbidity latent classes with several outcomes. 63.8% of participants were assigned to the "healthy" class, with minimum disease, 30% were classified under the "metabolic/stroke" class and 6% were assigned to the "cardiorespiratory/mental/arthritis" class. Significant cross-sectional associations were found between membership of both multimorbidity classes and poorer memory, quality of life, greater burden and more use of services. After 3 years of follow-up, the "metabolic/stroke" class was a significant predictor of lower levels of verbal fluency while the two multimorbidity classes predicted poor quality of life, problems in independent living, higher risk of hospitalization and greater use of health services. Common chronic conditions in older people cluster together in broad categories. These broad clusters are qualitatively distinct and are important predictors of several health and functioning outcomes. Future studies are needed to understand underlying mechanisms and common risk factors for patterns of multimorbidity and to propose more effective treatments.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
This study sought to identify multimorbidity patterns and determine the association between these latent classes with several outcomes, including health, functioning, disability, quality of life and use of services, at baseline and after 3 years of follow-up. We analyzed data from a representative Spanish cohort of 3541 non-institutionalized people aged 50 years old and over. Measures were taken at baseline and after 3 years of follow-up. Latent Class Analysis (LCA) was conducted using eleven common chronic conditions. Generalized linear models were conducted to determine the adjusted association of multimorbidity latent classes with several outcomes. 63.8% of participants were assigned to the "healthy" class, with minimum disease, 30% were classified under the "metabolic/stroke" class and 6% were assigned to the "cardiorespiratory/mental/arthritis" class. Significant cross-sectional associations were found between membership of both multimorbidity classes and poorer memory, quality of life, greater burden and more use of services. After 3 years of follow-up, the "metabolic/stroke" class was a significant predictor of lower levels of verbal fluency while the two multimorbidity classes predicted poor quality of life, problems in independent living, higher risk of hospitalization and greater use of health services. Common chronic conditions in older people cluster together in broad categories. These broad clusters are qualitatively distinct and are important predictors of several health and functioning outcomes. Future studies are needed to understand underlying mechanisms and common risk factors for patterns of multimorbidity and to propose more effective treatments.
Domenech-Abella, J; Mundo, J; Lara, E; Moneta, M V; Haro, J M; Olaya, B
The role of socio-economic status and neighborhood social capital on loneliness among older adults: evidence from the Sant Boi Aging Study Artículo de revista
En: Soc Psychiatry Psychiatr Epidemiol, vol. 52, no. 10, pp. 1237–1246, 2017.
Resumen | Enlaces | BibTeX | Etiquetas:
@article{pmid28646295b,
title = {The role of socio-economic status and neighborhood social capital on loneliness among older adults: evidence from the Sant Boi Aging Study},
author = {J Domenech-Abella and J Mundo and E Lara and M V Moneta and J M Haro and B Olaya},
url = {https://www.ncbi.nlm.nih.gov/pubmed/28646295},
year = {2017},
date = {2017-01-01},
journal = {Soc Psychiatry Psychiatr Epidemiol},
volume = {52},
number = {10},
pages = {1237--1246},
abstract = {The aim of the present study is to analyze the role of age in the association between socio-economic status (SES) and loneliness as well as the role of neighborhood social capital (NSC) in the association between individual social capital and loneliness. Data include a representative population-based sample from Sant Boi de Llobregat (a suburb of Barcelona) of 1124 adults aged 50 and over. Logistic regression models were used to analyze the survey data. Interactions between SES and age, and NSC and individual social capital were explored. Among the poorest older adults, older individuals showed a lower likelihood of loneliness (OR 0.09, 95% CI 0.02, 0.30, p < 0.05) compared with the youngest cohort after adjusting for covariates, while among the richest individuals there were no significant differences among age cohorts. Individuals living in an area with high NSC and high individual social capital showed a lower likelihood of loneliness (OR 0.36, 95% CI 0.17, 0.73, p < 0.05) compared with those with low individual social capital after adjusting for covariates. The effect of individual social capital was not significant among individuals living in an area with low NSC. Interventions focusing on low SES middle-aged (50-59 years old) individuals and those aiming to increase NSC could be effective strategies to reduce the prevalence of loneliness in older people.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The aim of the present study is to analyze the role of age in the association between socio-economic status (SES) and loneliness as well as the role of neighborhood social capital (NSC) in the association between individual social capital and loneliness. Data include a representative population-based sample from Sant Boi de Llobregat (a suburb of Barcelona) of 1124 adults aged 50 and over. Logistic regression models were used to analyze the survey data. Interactions between SES and age, and NSC and individual social capital were explored. Among the poorest older adults, older individuals showed a lower likelihood of loneliness (OR 0.09, 95% CI 0.02, 0.30, p < 0.05) compared with the youngest cohort after adjusting for covariates, while among the richest individuals there were no significant differences among age cohorts. Individuals living in an area with high NSC and high individual social capital showed a lower likelihood of loneliness (OR 0.36, 95% CI 0.17, 0.73, p < 0.05) compared with those with low individual social capital after adjusting for covariates. The effect of individual social capital was not significant among individuals living in an area with low NSC. Interventions focusing on low SES middle-aged (50-59 years old) individuals and those aiming to increase NSC could be effective strategies to reduce the prevalence of loneliness in older people.
Andres-Franch, M.; Galiana, A.; Sanchez-Hellin, V.; Ochoa, E.; Hernandez-Illan, E.; Lopez-Garcia, P.; Castillejo, A.; Castillejo, M. I.; Barbera, V. M.; Garcia-Dura, J.; Gomez-Romero, F. J.; Royo, G.; Soto, J. L.
Streptococcus gallolyticus infection in colorectal cancer and association with biological and clinical factors Artículo de revista
En: PLoS ONE, vol. 12, no. 3, pp. e0174305, 2017.
Resumen | Enlaces | BibTeX | Etiquetas:
@article{pmid28355283,
title = {Streptococcus gallolyticus infection in colorectal cancer and association with biological and clinical factors},
author = {Andres-Franch, M. and Galiana, A. and Sanchez-Hellin, V. and Ochoa, E. and Hernandez-Illan, E. and Lopez-Garcia, P. and Castillejo, A. and Castillejo, M. I. and Barbera, V. M. and Garcia-Dura, J. and Gomez-Romero, F. J. and Royo, G. and Soto, J. L. },
url = {https://www.ncbi.nlm.nih.gov/pubmed/28355283},
year = {2017},
date = {2017-01-01},
journal = {PLoS ONE},
volume = {12},
number = {3},
pages = {e0174305},
abstract = {There is an unambiguous association of Streptococcus gallolyticus infection with colorectal cancer, although there is limited information about epidemiology or interaction between molecular and environmental factors. We performed an original quantitative analysis of S. gallolyticus in unselected colorectal cancer patients (n = 190) and their association with clinical, pathological tumor molecular profiles (microsatellite instability, hypermethylator phenotype and chromosomal instability pathways), and other biological factors in colorectal tumor and normal tissues (cytomegalovirus and Epstein-Barr virus infection). We developed a new quantitative method to assess bacterial load. Analytical validation was reached with a very high sensitivity and specificity. Our results showed a 3.2% prevalence of S. gallolyticus infection in our unselected cohort of colorectal cancer cases (6/190). The average S. gallolyticus copy number was 7,018 (range 44-34,585). No previous reports relating to S. gallolyticus infection have been published for unselected cohorts of patients. Finally, and despite a low prevalence of S. gallolyticus in this study, we were able to define a specific association with tumor tissue (p = 0.03) and with coinfection with Epstein-Barr virus (p = 0.042; OR: 9.49; 95% IC: 1.1-82.9). The prevalence data provided will be very useful in the design of future studies, and will make it possible to estimate the sample size needed to assess precise objectives. In conclusion, our results show a low prevalence of S. gallolyticus infection in unselected colorectal cancer patients and an association of positive S. gallolyticus infection with tumor tissue and Epstein-Barr virus coinfection. Further studies will be needed to definitively assess the prevalence of S. gallolyticus in colorectal cancer and the associated clinicopathological and molecular profiles.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
There is an unambiguous association of Streptococcus gallolyticus infection with colorectal cancer, although there is limited information about epidemiology or interaction between molecular and environmental factors. We performed an original quantitative analysis of S. gallolyticus in unselected colorectal cancer patients (n = 190) and their association with clinical, pathological tumor molecular profiles (microsatellite instability, hypermethylator phenotype and chromosomal instability pathways), and other biological factors in colorectal tumor and normal tissues (cytomegalovirus and Epstein-Barr virus infection). We developed a new quantitative method to assess bacterial load. Analytical validation was reached with a very high sensitivity and specificity. Our results showed a 3.2% prevalence of S. gallolyticus infection in our unselected cohort of colorectal cancer cases (6/190). The average S. gallolyticus copy number was 7,018 (range 44-34,585). No previous reports relating to S. gallolyticus infection have been published for unselected cohorts of patients. Finally, and despite a low prevalence of S. gallolyticus in this study, we were able to define a specific association with tumor tissue (p = 0.03) and with coinfection with Epstein-Barr virus (p = 0.042; OR: 9.49; 95% IC: 1.1-82.9). The prevalence data provided will be very useful in the design of future studies, and will make it possible to estimate the sample size needed to assess precise objectives. In conclusion, our results show a low prevalence of S. gallolyticus infection in unselected colorectal cancer patients and an association of positive S. gallolyticus infection with tumor tissue and Epstein-Barr virus coinfection. Further studies will be needed to definitively assess the prevalence of S. gallolyticus in colorectal cancer and the associated clinicopathological and molecular profiles.
2016
Quiroga, M A; Roman, F J; Fuente, J De La; Privado, J; Colom, R
The Measurement of Intelligence in the XXI Century using Video Games Artículo de revista
En: Span J Psychol, vol. 19, pp. E89, 2016.
Resumen | Enlaces | BibTeX | Etiquetas:
@article{pmid27917731,
title = {The Measurement of Intelligence in the XXI Century using Video Games},
author = {M A Quiroga and F J Roman and J De La Fuente and J Privado and R Colom},
url = {https://www.ncbi.nlm.nih.gov/pubmed/27917731 },
year = {2016},
date = {2016-12-01},
journal = {Span J Psychol},
volume = {19},
pages = {E89},
abstract = {This paper reviews the use of video games for measuring intelligence differences and reports two studies analyzing the relationship between intelligence and performance on a leisure video game. In the first study, the main focus was to design an Intelligence Test using puzzles from the video game. Forty-seven young participants played "Professor Layton and the curious village"® for a maximum of 15 hours and completed a set of intelligence standardized tests. Results show that the time required for completing the game interacts with intelligence differences: the higher the intelligence, the lower the time (d = .91). Furthermore, a set of 41 puzzles showed excellent psychometric properties. The second study, done seven years later, confirmed the previous findings. We finally discuss the pros and cons of video games as tools for measuring cognitive abilities with commercial video games, underscoring that psychologists must develop their own intelligence video games and delineate their key features for the measurement devices of next generation.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
This paper reviews the use of video games for measuring intelligence differences and reports two studies analyzing the relationship between intelligence and performance on a leisure video game. In the first study, the main focus was to design an Intelligence Test using puzzles from the video game. Forty-seven young participants played "Professor Layton and the curious village"® for a maximum of 15 hours and completed a set of intelligence standardized tests. Results show that the time required for completing the game interacts with intelligence differences: the higher the intelligence, the lower the time (d = .91). Furthermore, a set of 41 puzzles showed excellent psychometric properties. The second study, done seven years later, confirmed the previous findings. We finally discuss the pros and cons of video games as tools for measuring cognitive abilities with commercial video games, underscoring that psychologists must develop their own intelligence video games and delineate their key features for the measurement devices of next generation.
Lopez-Garcia, P; Cristobal-Huerta, A; Espinoza, L Young; Molero, P; Sanchez-Pedreno, F Ortuno; Hernandez-Tamames, J A
The influence of the COMT genotype in the underlying functional brain activity of context processing in schizophrenia and in relatives Artículo de revista
En: Prog. Neuropsychopharmacol. Biol. Psychiatry, vol. 71, pp. 176–182, 2016.
Resumen | Enlaces | BibTeX | Etiquetas:
@article{pmid27421706,
title = {The influence of the COMT genotype in the underlying functional brain activity of context processing in schizophrenia and in relatives},
author = {P Lopez-Garcia and A Cristobal-Huerta and L Young Espinoza and P Molero and F Ortuno Sanchez-Pedreno and J A Hernandez-Tamames},
url = {https://www.ncbi.nlm.nih.gov/pubmed/27421706},
year = {2016},
date = {2016-11-01},
journal = {Prog. Neuropsychopharmacol. Biol. Psychiatry},
volume = {71},
pages = {176--182},
abstract = {Context processing deficits have been shown to be present in chronic and first episode schizophrenia patients and in their relatives. This cognitive process is linked to frontal functioning and is highly dependent on dopamine levels in the prefrontal cortex (PFC). The catechol-O-methyltransferase (COMT) enzyme plays a prominent role in regulating dopamine levels in PFC. Genotypic variations in the functional polymorphism Val(158)Met COMT appear to have an impact in dopamine signaling in the PFC of healthy subjects and schizophrenia patients. We aimed to explore the effect of the Val(158)Met COMT polymorphism on brain activation during the performance of a context processing task in healthy subjects, schizophrenia spectrum patients and their healthy relatives. 56 participants performed the Dot Probe Expectancy task (DPX) during the fMRI session. Subjects were genotyped and only the Val and Met homozygotes participated in the study. Schizophrenia spectrum patients and their relatives showed worse performance on context processing measures than healthy control subjects. The Val allele was associated with more context processing errors in healthy controls and in relatives compared to patients. There was a greater recruitment of frontal areas (supplementary motor area/cingulate gyrus) during context processing in patients relative to healthy controls. Met homozygotes subjects activated more frontal areas than Val homozygotes subjects. The Val(158)Met COMT polymorphism influences context processing and on its underlying brain activation, showing less recruitment of frontal areas in the subjects with the genotype associated to lower dopamine availability in PFC.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Context processing deficits have been shown to be present in chronic and first episode schizophrenia patients and in their relatives. This cognitive process is linked to frontal functioning and is highly dependent on dopamine levels in the prefrontal cortex (PFC). The catechol-O-methyltransferase (COMT) enzyme plays a prominent role in regulating dopamine levels in PFC. Genotypic variations in the functional polymorphism Val(158)Met COMT appear to have an impact in dopamine signaling in the PFC of healthy subjects and schizophrenia patients. We aimed to explore the effect of the Val(158)Met COMT polymorphism on brain activation during the performance of a context processing task in healthy subjects, schizophrenia spectrum patients and their healthy relatives. 56 participants performed the Dot Probe Expectancy task (DPX) during the fMRI session. Subjects were genotyped and only the Val and Met homozygotes participated in the study. Schizophrenia spectrum patients and their relatives showed worse performance on context processing measures than healthy control subjects. The Val allele was associated with more context processing errors in healthy controls and in relatives compared to patients. There was a greater recruitment of frontal areas (supplementary motor area/cingulate gyrus) during context processing in patients relative to healthy controls. Met homozygotes subjects activated more frontal areas than Val homozygotes subjects. The Val(158)Met COMT polymorphism influences context processing and on its underlying brain activation, showing less recruitment of frontal areas in the subjects with the genotype associated to lower dopamine availability in PFC.
Grande, I; Sanchez-Moreno, J; Torrent, C; Bonnin, C; Sole, B; Jimenez, E; Varo, C; Tabares-Seisdedos, R; Balanza-Martinez, V; Valls, E; Ayuso-Mateos, J; Vieta, E; Martinez-Aran, A
The possible resilience role of cognitive reserve in bipolar disorder Artículo de revista
En: European Neuropsychopharmacology, vol. 26, pp. S428-S429, 2016, ISSN: 0924-977X.
@article{ref1,
title = {The possible resilience role of cognitive reserve in bipolar disorder},
author = {I Grande and J Sanchez-Moreno and C Torrent and C Bonnin and B Sole and E Jimenez and C Varo and R Tabares-Seisdedos and V Balanza-Martinez and E Valls and J Ayuso-Mateos and E Vieta and A Martinez-Aran},
url = {http://dx.doi.org/10.1016/S0924-977X(16)31403-1},
doi = {10.1016/S0924-977X(16)31403-1},
issn = {0924-977X},
year = {2016},
date = {2016-10-03},
journal = {European Neuropsychopharmacology},
volume = {26},
pages = {S428-S429},
publisher = {Elsevier},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Lopez-Garcia, P; Niendam, T; Ashby, S; Pierce, K; Carter, C
Aggression in first episode psychosis: characteristics and associated factors Artículo de revista
En: European Neuropsychopharmacology, vol. 26, pp. S510, 2016, ISSN: 0924-977X.
@article{ref1b,
title = {Aggression in first episode psychosis: characteristics and associated factors},
author = {P Lopez-Garcia and T Niendam and S Ashby and K Pierce and C Carter},
url = {http://dx.doi.org/10.1016/S0924-977X(16)31533-4},
doi = {10.1016/S0924-977X(16)31533-4},
issn = {0924-977X},
year = {2016},
date = {2016-10-03},
journal = {European Neuropsychopharmacology},
volume = {26},
pages = {S510},
publisher = {Elsevier},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Lara, E; Haro, J M; Tang, M X; Manly, J; Stern, Y
Exploring the excess mortality due to depressive symptoms in a community-based sample: The role of Alzheimer's Disease Artículo de revista
En: J Affect Disord, vol. 202, pp. 163–170, 2016.
Resumen | Enlaces | BibTeX | Etiquetas:
@article{pmid27262638,
title = {Exploring the excess mortality due to depressive symptoms in a community-based sample: The role of Alzheimer's Disease},
author = {E Lara and J M Haro and M X Tang and J Manly and Y Stern},
url = {https://www.ncbi.nlm.nih.gov/pubmed/27262638},
year = {2016},
date = {2016-09-01},
journal = {J Affect Disord},
volume = {202},
pages = {163--170},
abstract = {Depression has been associated with increased risk of death. However, there is lack of studies exploring such relationship in the context of dementia. Given the high prevalence of both depression and Alzheimer's Disease (AD), investigating their temporal association with mortality is of public health relevance. Longitudinal data from the WHICAP study were analyzed (1958 individuals aged \^{a}‰¥65 years). Depressive symptoms were assessed with the 10-item Center for Epidemiologic Studies Depression Scale (CES-D). Respondents were identified as having AD if they satisfied the criteria of the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Cox regressions analyses were performed to determine the association between depressive symptoms and risk of all-cause mortality using the overall sample, and by AD status. Depressive symptoms were significantly associated with higher mortality risk after adjusting for all potential covariates in the overall sample (HR=1.22; 95% CI=1.02, 1.46) and in individuals with incident AD (HR=1.88; 95% CI=1.12, 3.18). The CES-D does not measure clinical depression but depressive symptomatology. Since those who were exposed to known risk factors for mortality are likely to die prematurely, our results may have been skewed to the individuals with longer survival. Strategies focusing on prevention and early treatment of depression in the elderly may have a beneficial effect not only on patient quality of life and disability, but may also increase survival in the context of AD.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Depression has been associated with increased risk of death. However, there is lack of studies exploring such relationship in the context of dementia. Given the high prevalence of both depression and Alzheimer's Disease (AD), investigating their temporal association with mortality is of public health relevance. Longitudinal data from the WHICAP study were analyzed (1958 individuals aged ≥65 years). Depressive symptoms were assessed with the 10-item Center for Epidemiologic Studies Depression Scale (CES-D). Respondents were identified as having AD if they satisfied the criteria of the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Cox regressions analyses were performed to determine the association between depressive symptoms and risk of all-cause mortality using the overall sample, and by AD status. Depressive symptoms were significantly associated with higher mortality risk after adjusting for all potential covariates in the overall sample (HR=1.22; 95% CI=1.02, 1.46) and in individuals with incident AD (HR=1.88; 95% CI=1.12, 3.18). The CES-D does not measure clinical depression but depressive symptomatology. Since those who were exposed to known risk factors for mortality are likely to die prematurely, our results may have been skewed to the individuals with longer survival. Strategies focusing on prevention and early treatment of depression in the elderly may have a beneficial effect not only on patient quality of life and disability, but may also increase survival in the context of AD.
Tyrovolas, S; Koyanagi, A; Olaya, B; Ayuso-Mateos, J L; Miret, M; Chatterji, S; Tobiasz-Adamczyk, B; Koskinen, S; Leonardi, M; Haro, J M
Factors associated with skeletal muscle mass, sarcopenia, and sarcopenic obesity in older adults: a multi-continent study Artículo de revista
En: J Cachexia Sarcopenia Muscle, vol. 7, no. 3, pp. 312–321, 2016.
Resumen | Enlaces | BibTeX | Etiquetas:
@article{pmid27239412,
title = {Factors associated with skeletal muscle mass, sarcopenia, and sarcopenic obesity in older adults: a multi-continent study},
author = {S Tyrovolas and A Koyanagi and B Olaya and J L Ayuso-Mateos and M Miret and S Chatterji and B Tobiasz-Adamczyk and S Koskinen and M Leonardi and J M Haro},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864288/},
year = {2016},
date = {2016-06-01},
journal = {J Cachexia Sarcopenia Muscle},
volume = {7},
number = {3},
pages = {312--321},
abstract = {The aim of this study was to evaluate the factors associated with low skeletal muscle mass (SMM), sarcopenia, and sarcopenic obesity using nationally representative samples of people aged \^{a}‰¥65 years from diverse geographical regions of the world. Data were available for 18 363 people aged \^{a}‰¥65 years who participated in the Collaborative Research on Ageing in Europe survey conducted in Finland, Poland, and Spain, and the World Health Organization Study on global AGEing and adult health survey conducted in China, Ghana, India, Mexico, Russia, and South Africa, between 2007 and 2012. A skeletal muscle mass index (SMI) was created to reflect SMM. SMM, SMI, and percent body fat (%BF) were calculated with specific indirect population formulas. These estimates were based on age, sex, weight, height, and race. Sarcopenia and sarcopenic obesity were defined with specific cut-offs. The prevalence of sarcopenia ranged from 12.6% (Poland) to 17.5% (India), and that of sarcopenic obesity ranged from 1.3% (India) to 11.0% (Spain). Higher %BF was associated with lower SMM in all countries, and with sarcopenia in five countries (p < 0.001). Compared to high levels of physical activity, low levels were related with higher odds for sarcopenia [OR 1.36 (95%CI 1.11-1.67)] and sarcopenic obesity [OR 1.80 (95%CI 1.23-2.64)] in the overall sample. Also, a dose-dependent association between higher numbers of chronic diseases and sarcopenic obesity was observed. Physical activity and body composition changes such as high %BF are key factors for the prevention of sarcopenia syndrome.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The aim of this study was to evaluate the factors associated with low skeletal muscle mass (SMM), sarcopenia, and sarcopenic obesity using nationally representative samples of people aged ≥65 years from diverse geographical regions of the world. Data were available for 18 363 people aged ≥65 years who participated in the Collaborative Research on Ageing in Europe survey conducted in Finland, Poland, and Spain, and the World Health Organization Study on global AGEing and adult health survey conducted in China, Ghana, India, Mexico, Russia, and South Africa, between 2007 and 2012. A skeletal muscle mass index (SMI) was created to reflect SMM. SMM, SMI, and percent body fat (%BF) were calculated with specific indirect population formulas. These estimates were based on age, sex, weight, height, and race. Sarcopenia and sarcopenic obesity were defined with specific cut-offs. The prevalence of sarcopenia ranged from 12.6% (Poland) to 17.5% (India), and that of sarcopenic obesity ranged from 1.3% (India) to 11.0% (Spain). Higher %BF was associated with lower SMM in all countries, and with sarcopenia in five countries (p < 0.001). Compared to high levels of physical activity, low levels were related with higher odds for sarcopenia [OR 1.36 (95%CI 1.11-1.67)] and sarcopenic obesity [OR 1.80 (95%CI 1.23-2.64)] in the overall sample. Also, a dose-dependent association between higher numbers of chronic diseases and sarcopenic obesity was observed. Physical activity and body composition changes such as high %BF are key factors for the prevention of sarcopenia syndrome.
Anaya, C.; Torrent, C.; Caballero, F. F.; Vieta, E.; Bonnin, C. d. e. l. M.; Ayuso-Mateos, J. L.; Alegria, A.; Amann, B. L.; Al-Halabi, S.; Alonso-Lana, S.; Arango, C.; Balanza-Martinez, V.; Barbeito, S.; Bobes, J.; Diaz-Caneja, C.; Cerrillo, E.; Colom, F.; Correa, P.; Crespo, J. M.; Custal, N.; Fernandez, P.; Fernandez, M.; Fuentes-Dura, I.; Garcia-Portilla, M. P.; Galvan, G.; Gonzalez-Pinto, A.; Ibanez, A.; Isella, S.; Jimenez, E.; Landin-Romero, R.; Martinez-Aran, A.; Mayoral, M.; Menchon, J. M.; Merchan-Naranjo, J.; Ortiz-Gil, J.; Pacchiarotti, I.; Reyes, R.; Rosa, A. R.; Rapado-Castro, M.; Reinares, M.; Rodao, J. M.; Saiz, P. A.; Sanchez-Moreno, J.; Salamero, M.; Segura, B.; Selva-Vera, G.; Saiz-Ruiz, J.; Sole, B.; Soria, V.; Subira, M.; Tabares-Seisdedos, R.; Ugarte, A.; Valle, J.; Vega, P.
Cognitive reserve in bipolar disorder: relation to cognition, psychosocial functioning and quality of life Artículo de revista
En: vol. 133, no. 5, pp. 386–398, 2016.
Resumen | Enlaces | BibTeX | Etiquetas:
@article{pmid26719018,
title = {Cognitive reserve in bipolar disorder: relation to cognition, psychosocial functioning and quality of life},
author = {Anaya, C. and Torrent, C. and Caballero, F. F. and Vieta, E. and Bonnin, C. d. e. l. M. and Ayuso-Mateos, J. L. and Alegria, A. and Amann, B. L. and Al-Halabi, S. and Alonso-Lana, S. and Arango, C. and Balanza-Martinez, V. and Barbeito, S. and Bobes, J. and Diaz-Caneja, C. and Cerrillo, E. and Colom, F. and Correa, P. and Crespo, J. M. and Custal, N. and Fernandez, P. and Fernandez, M. and Fuentes-Dura, I. and Garcia-Portilla, M. P. and Galvan, G. and Gonzalez-Pinto, A. and Ibanez, A. and Isella, S. and Jimenez, E. and Landin-Romero, R. and Martinez-Aran, A. and Mayoral, M. and Menchon, J. M. and Merchan-Naranjo, J. and Ortiz-Gil, J. and Pacchiarotti, I. and Reyes, R. and Rosa, A. R. and Rapado-Castro, M. and Reinares, M. and Rodao, J. M. and Saiz, P. A. and Sanchez-Moreno, J. and Salamero, M. and Segura, B. and Selva-Vera, G. and Saiz-Ruiz, J. and Sole, B. and Soria, V. and Subira, M. and Tabares-Seisdedos, R. and Ugarte, A. and Valle, J. and Vega, P. },
url = {https://www.ncbi.nlm.nih.gov/pubmed/26719018},
year = {2016},
date = {2016-05-01},
volume = {133},
number = {5},
pages = {386--398},
abstract = {Cognitive reserve (CR) is a concept that was postulated as a protective factor for some clinical symptoms after the observation that there is not a direct relationship between the degree of brain damage and its clinical manifestation. This study aimed to explore the association between CR and the main outcomes in bipolar disorder (BD): cognitive functions, psychosocial functioning and perceived quality of life. A sample of 224 euthymic bipolar patients was assessed with a neuropsychological battery, the Functioning Assessment Short Test and the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). CR was calculated through three proxies: estimated premorbid Intelligent Quotient, educational level and occupational attainment. Relationships between CR and cognitive functions, psychosocial functioning and quality of life were assessed by multiple linear regression models. Higher CR was associated with better cognitive functioning (P < 0.001 in processing speed, working memory, verbal and visual memory, and executive function; P = 0.026 in attention) and better psychosocial functioning (P = 0.008). For quality of life, CR was positively associated with the physical component of the SF-36 (P = 0.016) but negatively associated with the mental component (P = 0.004). The results suggest that CR may play an important role in the course and prognosis of bipolar patients and it should be considered in both clinical and research settings related to BD.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Cognitive reserve (CR) is a concept that was postulated as a protective factor for some clinical symptoms after the observation that there is not a direct relationship between the degree of brain damage and its clinical manifestation. This study aimed to explore the association between CR and the main outcomes in bipolar disorder (BD): cognitive functions, psychosocial functioning and perceived quality of life. A sample of 224 euthymic bipolar patients was assessed with a neuropsychological battery, the Functioning Assessment Short Test and the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). CR was calculated through three proxies: estimated premorbid Intelligent Quotient, educational level and occupational attainment. Relationships between CR and cognitive functions, psychosocial functioning and quality of life were assessed by multiple linear regression models. Higher CR was associated with better cognitive functioning (P < 0.001 in processing speed, working memory, verbal and visual memory, and executive function; P = 0.026 in attention) and better psychosocial functioning (P = 0.008). For quality of life, CR was positively associated with the physical component of the SF-36 (P = 0.016) but negatively associated with the mental component (P = 0.004). The results suggest that CR may play an important role in the course and prognosis of bipolar patients and it should be considered in both clinical and research settings related to BD.
Tyrovolas, S; Koyanagi, A; Lara, E; Santini, Z I; Haro, J M
Mild cognitive impairment is associated with falls among older adults: Findings from the Irish Longitudinal Study on Ageing (TILDA) Artículo de revista
En: Exp. Gerontol., vol. 75, pp. 42–47, 2016.
Resumen | Enlaces | BibTeX | Etiquetas:
@article{pmid26707711,
title = {Mild cognitive impairment is associated with falls among older adults: Findings from the Irish Longitudinal Study on Ageing (TILDA)},
author = {S Tyrovolas and A Koyanagi and E Lara and Z I Santini and J M Haro},
url = {https://www.ncbi.nlm.nih.gov/pubmed/26707711},
year = {2016},
date = {2016-03-01},
journal = {Exp. Gerontol.},
volume = {75},
pages = {42--47},
abstract = {The role of mild cognitive impairment (MCI) on falls among older adults remains under-investigated. The aim of this study was to evaluate the association between MCI and number of falls or occurrence of non-accidental falls among older adults. Data from the first wave of the Irish longitudinal Study on Ageing (TILDA) was analysed. The analytical sample consisted of 5364 individuals aged \^{a}‰¥ 50 years. MCI was defined as: Montreal Cognitive Assessment (MoCA) score<26; the presence of subjective cognitive complaints; Mini-Mental State Examination (MMSE) score \^{a}‰¥ 14; and no limitations in activities of daily living (ADL). Multivariable Poisson and logistic regression analyses were conducted to assess the association between MCI and number of falls or the presence of non-accidental falls in the past 12 months. The prevalence of MCI was 10.1%. In the fully-adjusted model, MCI was associated with a higher rate of falls (PR=1.41 95%CI=1.05-1.89) and odds for non-accidental falls in the past 12 months (OR=1.67 95%CI=1.07-2.61). Muscle strength and performance indicators, and medical health conditions were influential factors in the association between MCI and falls but did not fully explain the association. MCI is related with higher rates of falls and the occurrence of non-accidental falls among older adults. Future studies are warranted to clarify the underlying mechanism linking MCI and falls, and to establish interventions targeting MCI to reduce the risk of falls.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The role of mild cognitive impairment (MCI) on falls among older adults remains under-investigated. The aim of this study was to evaluate the association between MCI and number of falls or occurrence of non-accidental falls among older adults. Data from the first wave of the Irish longitudinal Study on Ageing (TILDA) was analysed. The analytical sample consisted of 5364 individuals aged ≥ 50 years. MCI was defined as: Montreal Cognitive Assessment (MoCA) score<26; the presence of subjective cognitive complaints; Mini-Mental State Examination (MMSE) score ≥ 14; and no limitations in activities of daily living (ADL). Multivariable Poisson and logistic regression analyses were conducted to assess the association between MCI and number of falls or the presence of non-accidental falls in the past 12 months. The prevalence of MCI was 10.1%. In the fully-adjusted model, MCI was associated with a higher rate of falls (PR=1.41 95%CI=1.05-1.89) and odds for non-accidental falls in the past 12 months (OR=1.67 95%CI=1.07-2.61). Muscle strength and performance indicators, and medical health conditions were influential factors in the association between MCI and falls but did not fully explain the association. MCI is related with higher rates of falls and the occurrence of non-accidental falls among older adults. Future studies are warranted to clarify the underlying mechanism linking MCI and falls, and to establish interventions targeting MCI to reduce the risk of falls.
Freeman, A; Tyrovolas, S; Koyanagi, A; Chatterji, S; Leonardi, M; Ayuso-Mateos, J L; Tobiasz-Adamczyk, B; Koskinen, S; Rummel-Kluge, C; Haro, J M
The role of socio-economic status in depression: results from the COURAGE (aging survey in Europe) Artículo de revista
En: BMC Public Health, vol. 16, no. 1, pp. 1098, 2016.
@article{pmid27760538,
title = {The role of socio-economic status in depression: results from the COURAGE (aging survey in Europe)},
author = {A Freeman and S Tyrovolas and A Koyanagi and S Chatterji and M Leonardi and J L Ayuso-Mateos and B Tobiasz-Adamczyk and S Koskinen and C Rummel-Kluge and J M Haro},
year = {2016},
date = {2016-01-01},
journal = {BMC Public Health},
volume = {16},
number = {1},
pages = {1098},
abstract = {Low socio-economic status (SES) has been found to be associated with a higher prevalence of depression. However, studies that have investigated this association have been limited in their national scope, have analyzed different components of SES separately, and have not used standardized definitions or measurements across populations. The aim of the current study was to evaluate the association between SES and depression across three European countries that represent different regions across Europe, using standardized procedures and measurements and a composite score for SES. Nationally-representative data on 10,800 individuals aged \^{a}‰¥18 from the Collaborative Research on Ageing in Europe (COURAGE) survey conducted in Finland, Poland and Spain were analyzed in this cross-sectional study. An adapted version of the Composite International Diagnostic Interview was used to identify the presence of depression, and SES was computed by using the combined scores of the total number of years educated (0-22) and the quintiles of the country-specific income level of the household (1-5). Multivariable logistic regression was used to assess the association between SES and depression. Findings reveal a significant association between depression and SES across all countries (p \^{a}‰¤ 0.001). After adjusting for confounders, the odds of depression were significantly decreased for every unit increase in the SES index for Finland, Poland and Spain. Additionally, higher education significantly decreased the odds for depression in each country, but income did not. The SES index seems to predict depression symptomatology across European countries. Taking SES into account may be an important factor in the development of depression prevention strategies across Europe.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Low socio-economic status (SES) has been found to be associated with a higher prevalence of depression. However, studies that have investigated this association have been limited in their national scope, have analyzed different components of SES separately, and have not used standardized definitions or measurements across populations. The aim of the current study was to evaluate the association between SES and depression across three European countries that represent different regions across Europe, using standardized procedures and measurements and a composite score for SES. Nationally-representative data on 10,800 individuals aged ≥18 from the Collaborative Research on Ageing in Europe (COURAGE) survey conducted in Finland, Poland and Spain were analyzed in this cross-sectional study. An adapted version of the Composite International Diagnostic Interview was used to identify the presence of depression, and SES was computed by using the combined scores of the total number of years educated (0-22) and the quintiles of the country-specific income level of the household (1-5). Multivariable logistic regression was used to assess the association between SES and depression. Findings reveal a significant association between depression and SES across all countries (p ≤ 0.001). After adjusting for confounders, the odds of depression were significantly decreased for every unit increase in the SES index for Finland, Poland and Spain. Additionally, higher education significantly decreased the odds for depression in each country, but income did not. The SES index seems to predict depression symptomatology across European countries. Taking SES into account may be an important factor in the development of depression prevention strategies across Europe.
Raggi, A; Corso, B; Minicuci, N; Quintas, R; Sattin, D; Torres, L De; Chatterji, S; Frisoni, G B; Haro, J M; Koskinen, S; Martinuzzi, A; Miret, M; Tobiasz-Adamczyk, B; Leonardi, M
Determinants of Quality of Life in Ageing Populations: Results from a Cross-Sectional Study in Finland, Poland and Spain Artículo de revista
En: PLoS ONE, vol. 11, no. 7, pp. e0159293, 2016.
Resumen | Enlaces | BibTeX | Etiquetas:
@article{pmid27434374,
title = {Determinants of Quality of Life in Ageing Populations: Results from a Cross-Sectional Study in Finland, Poland and Spain},
author = {A Raggi and B Corso and N Minicuci and R Quintas and D Sattin and L De Torres and S Chatterji and G B Frisoni and J M Haro and S Koskinen and A Martinuzzi and M Miret and B Tobiasz-Adamczyk and M Leonardi},
url = {https://www.ncbi.nlm.nih.gov/pubmed/27434374},
year = {2016},
date = {2016-01-01},
journal = {PLoS ONE},
volume = {11},
number = {7},
pages = {e0159293},
abstract = {To comprehensively identify the determinants of quality of life (QoL) in a population study sample of persons aged 18-50 and 50+. In this observational, cross-sectional study, QoL was measured with the WHOQOL-AGE, a brief instrument designed to measure QoL in older adults. Eight hierarchical regression models were performed to identify determinants of QoL. Variables were entered in the following order: Sociodemographic; Health Habits; Chronic Conditions; Health State description; Vision and Hearing; Social Networks; Built Environment. In the final model, significant variables were retained. The final model was re-run using data from the three countries separately. Complete data were available for 5639 participants, mean age 46.3 (SD 18.4). The final model accounted for 45% of QoL variation and the most relevant contribution was given by sociodemographic data (particularly age, education level and living in Finland: 17.9% explained QoL variation), chronic conditions (particularly depression: 4.6%) and a wide and rich social network (4.6%). Other determinants were presence of disabling pain, learning difficulties and visual problems, and living in usable house that is perceived as non-risky. Some variables were specifically associated to QoL in single countries: age in Poland, alcohol consumption in Spain, angina in Finland, depression in Spain, and self-reported sadness both in Finland and Poland, but not in Spain. Other were commonly associated to QoL: smoking status, bodily aches, being emotionally affected by health problems, good social network and home characteristics. Our results highlight the importance of modifiable determinants of QoL, and provide public health indications that could support concrete actions at country level. In particular, smoking cessation, increasing the level of physical activity, improving social network ties and applying universal design approach to houses and environmental infrastructures could potentially increase QoL of ageing population.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
To comprehensively identify the determinants of quality of life (QoL) in a population study sample of persons aged 18-50 and 50+. In this observational, cross-sectional study, QoL was measured with the WHOQOL-AGE, a brief instrument designed to measure QoL in older adults. Eight hierarchical regression models were performed to identify determinants of QoL. Variables were entered in the following order: Sociodemographic; Health Habits; Chronic Conditions; Health State description; Vision and Hearing; Social Networks; Built Environment. In the final model, significant variables were retained. The final model was re-run using data from the three countries separately. Complete data were available for 5639 participants, mean age 46.3 (SD 18.4). The final model accounted for 45% of QoL variation and the most relevant contribution was given by sociodemographic data (particularly age, education level and living in Finland: 17.9% explained QoL variation), chronic conditions (particularly depression: 4.6%) and a wide and rich social network (4.6%). Other determinants were presence of disabling pain, learning difficulties and visual problems, and living in usable house that is perceived as non-risky. Some variables were specifically associated to QoL in single countries: age in Poland, alcohol consumption in Spain, angina in Finland, depression in Spain, and self-reported sadness both in Finland and Poland, but not in Spain. Other were commonly associated to QoL: smoking status, bodily aches, being emotionally affected by health problems, good social network and home characteristics. Our results highlight the importance of modifiable determinants of QoL, and provide public health indications that could support concrete actions at country level. In particular, smoking cessation, increasing the level of physical activity, improving social network ties and applying universal design approach to houses and environmental infrastructures could potentially increase QoL of ageing population.
Lara, E; Koyanagi, A; Olaya, B; Lobo, A; Miret, M; Tyrovolas, S; Ayuso-Mateos, J L; Haro, J M
Mild cognitive impairment in a Spanish representative sample: prevalence and associated factors Artículo de revista
En: Int J Geriatr Psychiatry, vol. 31, no. 8, pp. 858–867, 2016.
@article{pmid26923809,
title = {Mild cognitive impairment in a Spanish representative sample: prevalence and associated factors},
author = {E Lara and A Koyanagi and B Olaya and A Lobo and M Miret and S Tyrovolas and J L Ayuso-Mateos and J M Haro},
year = {2016},
date = {2016-01-01},
journal = {Int J Geriatr Psychiatry},
volume = {31},
number = {8},
pages = {858--867},
abstract = {Given the limitations of treatments for dementia, the characterisation of the early stages of dementia is crucial for the development of preventive programmes and interventions. We aimed to estimate the prevalence of mild cognitive impairment (MCI) and examine its medical and lifestyle correlates in a nationally representative sample of the Spanish population. A total of 3625 participants (\^{a}‰¥50 years of age) were interviewed in a cross-sectional study. MCI was defined as the presence of cognitive concerns, the objective evidence of impairment in one or more cognitive domains, the preservation of independence in functional abilities and no dementia. Participants were also asked to provide sociodemographic, health status and lifestyle information. Logistic regression analyses were performed using the overall sample and by age groups. The overall prevalence of MCI was 9.6%, with higher rates in older people and women. In the overall model, after adjustment for potential confounders, depression [odds ratio (OR) = 1.79; 95% confidence interval (CI) = 1.21, 2.66], diabetes (OR = 1.43; 95% CI = 1.05, 1.95), sleep disturbances (OR = 1.66; 95% CI = 1.09, 2.55) and low level of physical activity (OR = 1.71; 95% CI = 1.26, 2.31) were associated with significantly higher odds for MCI. When stratified by age groups, depression (OR = 2.41; 95% CI = 1.35, 4.31), stroke (OR = 3.77; 95% CI = 1.44, 9.83) and obesity (OR = 2.06; 95% CI = 1.20, 3.53) were significantly associated with MCI in middle-aged participants (50-64 years), whereas low level of physical activity (OR = 1.85; 95% CI = 1.32, 2.59) and sleep disturbances (OR = 1.79; 95% CI = 1.05, 3.05) were associated with MCI in individuals aged 65+ years. Significant associations between MCI and psychological, cardiovascular and lifestyle factors were found. Targeting modifiable risk factors might reduce the risk for MCI and subsequent dementia.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Given the limitations of treatments for dementia, the characterisation of the early stages of dementia is crucial for the development of preventive programmes and interventions. We aimed to estimate the prevalence of mild cognitive impairment (MCI) and examine its medical and lifestyle correlates in a nationally representative sample of the Spanish population. A total of 3625 participants (≥50 years of age) were interviewed in a cross-sectional study. MCI was defined as the presence of cognitive concerns, the objective evidence of impairment in one or more cognitive domains, the preservation of independence in functional abilities and no dementia. Participants were also asked to provide sociodemographic, health status and lifestyle information. Logistic regression analyses were performed using the overall sample and by age groups. The overall prevalence of MCI was 9.6%, with higher rates in older people and women. In the overall model, after adjustment for potential confounders, depression [odds ratio (OR) = 1.79; 95% confidence interval (CI) = 1.21, 2.66], diabetes (OR = 1.43; 95% CI = 1.05, 1.95), sleep disturbances (OR = 1.66; 95% CI = 1.09, 2.55) and low level of physical activity (OR = 1.71; 95% CI = 1.26, 2.31) were associated with significantly higher odds for MCI. When stratified by age groups, depression (OR = 2.41; 95% CI = 1.35, 4.31), stroke (OR = 3.77; 95% CI = 1.44, 9.83) and obesity (OR = 2.06; 95% CI = 1.20, 3.53) were significantly associated with MCI in middle-aged participants (50-64 years), whereas low level of physical activity (OR = 1.85; 95% CI = 1.32, 2.59) and sleep disturbances (OR = 1.79; 95% CI = 1.05, 3.05) were associated with MCI in individuals aged 65+ years. Significant associations between MCI and psychological, cardiovascular and lifestyle factors were found. Targeting modifiable risk factors might reduce the risk for MCI and subsequent dementia.
Kamenov, K; Cabello, M; Caballero, F F; Cieza, A; Sabariego, C; Raggi, A; Anczewska, M; Pitkanen, T; Ayuso-Mateos, J L
Factors Related to Social Support in Neurological and Mental Disorders Artículo de revista
En: PLoS ONE, vol. 11, no. 2, pp. e0149356, 2016.
@article{pmid26900847,
title = {Factors Related to Social Support in Neurological and Mental Disorders},
author = {K Kamenov and M Cabello and F F Caballero and A Cieza and C Sabariego and A Raggi and M Anczewska and T Pitkanen and J L Ayuso-Mateos},
year = {2016},
date = {2016-01-01},
journal = {PLoS ONE},
volume = {11},
number = {2},
pages = {e0149356},
abstract = {Despite the huge body of research on social support, literature has been primarily focused on its beneficial role for both physical and mental health. It is still unclear why people with mental and neurological disorders experience low levels of social support. The main objective of this study was to explore what are the strongest factors related to social support and how do they interact with each other in neuropsychiatric disorders. The study used cross-sectional data from 722 persons suffering from dementia, depression, epilepsy, migraine, multiple sclerosis, Parkinson's disease, schizophrenia, stroke, and substance use disorders. Multiple linear regressions showed that disability was the strongest factor for social support. Extraversion and agreeableness were significant personality variables, but when the interaction terms between personality traits and disability were included, disability remained the only significant variable. Moreover, level of disability mediated the relationship between personality (extraversion and agreeableness) and level of social support. Moderation analysis revealed that people that had mental disorders experienced lower levels of support when being highly disabled compared to people with neurological disorders. Unlike previous literature, focused on increasing social support as the origin of improving disability, this study suggested that interventions improving day-to-day functioning or maladaptive personality styles might also have an effect on the way people perceive social support. Future longitudinal research, however, is warranted to explore causality.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Despite the huge body of research on social support, literature has been primarily focused on its beneficial role for both physical and mental health. It is still unclear why people with mental and neurological disorders experience low levels of social support. The main objective of this study was to explore what are the strongest factors related to social support and how do they interact with each other in neuropsychiatric disorders. The study used cross-sectional data from 722 persons suffering from dementia, depression, epilepsy, migraine, multiple sclerosis, Parkinson's disease, schizophrenia, stroke, and substance use disorders. Multiple linear regressions showed that disability was the strongest factor for social support. Extraversion and agreeableness were significant personality variables, but when the interaction terms between personality traits and disability were included, disability remained the only significant variable. Moreover, level of disability mediated the relationship between personality (extraversion and agreeableness) and level of social support. Moderation analysis revealed that people that had mental disorders experienced lower levels of support when being highly disabled compared to people with neurological disorders. Unlike previous literature, focused on increasing social support as the origin of improving disability, this study suggested that interventions improving day-to-day functioning or maladaptive personality styles might also have an effect on the way people perceive social support. Future longitudinal research, however, is warranted to explore causality.
Olaya, B.; Moneta, M. V.; Koyanagi, A.; Lara, E.; Miret, M.; Ayuso-Mateos, J. L.; Chatterji, S.; Leonardi, M.; Koskinen, S.; Tobiasz-Adamczyk, B.; Lobo, A.; Haro, J. M.
The joint association of depression and cognitive function with severe disability among community-dwelling older adults in Finland, Poland and Spain Artículo de revista
En: Exp. Gerontol., vol. 76, pp. 39–45, 2016.
@article{pmid26805608,
title = {The joint association of depression and cognitive function with severe disability among community-dwelling older adults in Finland, Poland and Spain},
author = {Olaya, B. and Moneta, M. V. and Koyanagi, A. and Lara, E. and Miret, M. and Ayuso-Mateos, J. L. and Chatterji, S. and Leonardi, M. and Koskinen, S. and Tobiasz-Adamczyk, B. and Lobo, A. and Haro, J. M. },
year = {2016},
date = {2016-01-01},
journal = {Exp. Gerontol.},
volume = {76},
pages = {39--45},
abstract = {To explore the joint association of depression and cognitive function with severe disability in nationally-representative samples of community-dwelling adults aged 50 years and older from Finland, Poland and Spain. Cross-sectional. Community-based. Population-based sample of 7987 non-institutionalized adults aged 50 and older. The outcome was severe disability, defined as \^{a}‰¥ 90th percentile of the 12-item version of the World Health Organization Disability Assessment Schedule (WHODAS 2.0). Past 12-month DSM-IV major depressive disorder was assessed with the depression module of the WHO Composite International Diagnostic Interview (CIDI). A global cognitive function score was obtained through neuropsychological tests. Product terms between depression and cognition were introduced in multivariable logistic regression models to test for interaction. Lower cognitive function and depression were both significantly associated with severe disability in all countries. A significant interaction was only found in Finland where the ORs (95% CIs) of depression for severe disability at the 25th (worse), 50th, and 75th (better) percentiles of cognitive function were 7.26 (4.28-12.32), 11.1 (6.7-18.38), and 17.56 (9.29-33.2), respectively. People with depression and cognitive decline are likely to benefit from the usual evidence-based treatments to reduce the burden of disability. However, in Finland, those with better cognitive function may benefit from more aggressive depression treatment. Future research is warranted to assess whether our results may be replicated.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
To explore the joint association of depression and cognitive function with severe disability in nationally-representative samples of community-dwelling adults aged 50 years and older from Finland, Poland and Spain. Cross-sectional. Community-based. Population-based sample of 7987 non-institutionalized adults aged 50 and older. The outcome was severe disability, defined as ≥ 90th percentile of the 12-item version of the World Health Organization Disability Assessment Schedule (WHODAS 2.0). Past 12-month DSM-IV major depressive disorder was assessed with the depression module of the WHO Composite International Diagnostic Interview (CIDI). A global cognitive function score was obtained through neuropsychological tests. Product terms between depression and cognition were introduced in multivariable logistic regression models to test for interaction. Lower cognitive function and depression were both significantly associated with severe disability in all countries. A significant interaction was only found in Finland where the ORs (95% CIs) of depression for severe disability at the 25th (worse), 50th, and 75th (better) percentiles of cognitive function were 7.26 (4.28-12.32), 11.1 (6.7-18.38), and 17.56 (9.29-33.2), respectively. People with depression and cognitive decline are likely to benefit from the usual evidence-based treatments to reduce the burden of disability. However, in Finland, those with better cognitive function may benefit from more aggressive depression treatment. Future research is warranted to assess whether our results may be replicated.
Keeley, J W; Reed, G M; Roberts, M C; Evans, S C; Medina-Mora, M E; Robles, R; Rebello, T; Sharan, P; Gureje, O; First, M B; Andrews, H F; Ayuso-Mateos, J L; Gaebel, W; Zielasek, J; Saxena, S
Developing a science of clinical utility in diagnostic classification systems field study strategies for ICD-11 mental and behavioral disorders Artículo de revista
En: Am Psychol, vol. 71, no. 1, pp. 3–16, 2016.
Resumen | Enlaces | BibTeX | Etiquetas:
@article{pmid26766762,
title = {Developing a science of clinical utility in diagnostic classification systems field study strategies for ICD-11 mental and behavioral disorders},
author = {J W Keeley and G M Reed and M C Roberts and S C Evans and M E Medina-Mora and R Robles and T Rebello and P Sharan and O Gureje and M B First and H F Andrews and J L Ayuso-Mateos and W Gaebel and J Zielasek and S Saxena},
url = {https://www.ncbi.nlm.nih.gov/pubmed/26766762},
year = {2016},
date = {2016-01-01},
journal = {Am Psychol},
volume = {71},
number = {1},
pages = {3--16},
abstract = {The World Health Organization (WHO) Department of Mental Health and Substance Abuse has developed a systematic program of field studies to evaluate and improve the clinical utility of the proposed diagnostic guidelines for mental and behavioral disorders in the Eleventh Revision of the International Classification of Diseases and Related Health Problems (ICD-11). The clinical utility of a diagnostic classification is critical to its function as the interface between health encounters and health information, and to making the ICD-11 be a more effective tool for helping the WHO's 194 member countries, including the United States, reduce the global disease burden of mental disorders. This article describes the WHO's efforts to develop a science of clinical utility in regard to one of the two major classification systems for mental disorders. We present the rationale and methodologies for an integrated and complementary set of field study strategies, including large international surveys, formative field studies of the structure of clinicians' conceptualization of mental disorders, case-controlled field studies using experimental methodologies to evaluate the impact of proposed changes to the diagnostic guidelines on clinicians' diagnostic decision making, and ecological implementation field studies of clinical utility in the global settings in which the guidelines will ultimately be implemented. The results of these studies have already been used in making decisions about the structure and content of ICD-11. If clinical utility is indeed among the highest aims of diagnostic systems for mental disorders, as their developers routinely claim, future revision efforts should continue to build on these efforts. (PsycINFO Database Record},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The World Health Organization (WHO) Department of Mental Health and Substance Abuse has developed a systematic program of field studies to evaluate and improve the clinical utility of the proposed diagnostic guidelines for mental and behavioral disorders in the Eleventh Revision of the International Classification of Diseases and Related Health Problems (ICD-11). The clinical utility of a diagnostic classification is critical to its function as the interface between health encounters and health information, and to making the ICD-11 be a more effective tool for helping the WHO's 194 member countries, including the United States, reduce the global disease burden of mental disorders. This article describes the WHO's efforts to develop a science of clinical utility in regard to one of the two major classification systems for mental disorders. We present the rationale and methodologies for an integrated and complementary set of field study strategies, including large international surveys, formative field studies of the structure of clinicians' conceptualization of mental disorders, case-controlled field studies using experimental methodologies to evaluate the impact of proposed changes to the diagnostic guidelines on clinicians' diagnostic decision making, and ecological implementation field studies of clinical utility in the global settings in which the guidelines will ultimately be implemented. The results of these studies have already been used in making decisions about the structure and content of ICD-11. If clinical utility is indeed among the highest aims of diagnostic systems for mental disorders, as their developers routinely claim, future revision efforts should continue to build on these efforts. (PsycINFO Database Record
Rico-Uribe, L A; Caballero, F F; Olaya, B; Tobiasz-Adamczyk, B; Koskinen, S; Leonardi, M; Haro, J M; Chatterji, S; Ayuso-Mateos, J L; Miret, M
Loneliness, Social Networks, and Health: A Cross-Sectional Study in Three Countries Artículo de revista
En: PLoS ONE, vol. 11, no. 1, pp. e0145264, 2016.
@article{pmid26761205,
title = {Loneliness, Social Networks, and Health: A Cross-Sectional Study in Three Countries},
author = {L A Rico-Uribe and F F Caballero and B Olaya and B Tobiasz-Adamczyk and S Koskinen and M Leonardi and J M Haro and S Chatterji and J L Ayuso-Mateos and M Miret},
year = {2016},
date = {2016-01-01},
journal = {PLoS ONE},
volume = {11},
number = {1},
pages = {e0145264},
abstract = {It is widely recognized that social networks and loneliness have effects on health. The present study assesses the differential association that the components of the social network and the subjective perception of loneliness have with health, and analyzes whether this association is different across different countries. A total of 10 800 adults were interviewed in Finland, Poland and Spain. Loneliness was assessed by means of the 3-item UCLA Loneliness Scale. Individuals' social networks were measured by asking about the number of members in the network, how often they had contacts with these members, and whether they had a close relationship. The differential association of loneliness and the components of the social network with health was assessed by means of hierarchical linear regression models, controlling for relevant covariates. In all three countries, loneliness was the variable most strongly correlated with health after controlling for depression, age, and other covariates. Loneliness contributed more strongly to health than any component of the social network. The relationship between loneliness and health was stronger in Finland (|\^{I}²| = 0.25) than in Poland (|\^{I}²| = 0.16) and Spain (|\^{I}²| = 0.18). Frequency of contact was the only component of the social network that was moderately correlated with health. Loneliness has a stronger association with health than the components of the social network. This association is similar in three different European countries with different socio-economic and health characteristics and welfare systems. The importance of evaluating and screening feelings of loneliness in individuals with health problems should be taken into account. Further studies are needed in order to be able to confirm the associations found in the present study and infer causality.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
It is widely recognized that social networks and loneliness have effects on health. The present study assesses the differential association that the components of the social network and the subjective perception of loneliness have with health, and analyzes whether this association is different across different countries. A total of 10 800 adults were interviewed in Finland, Poland and Spain. Loneliness was assessed by means of the 3-item UCLA Loneliness Scale. Individuals' social networks were measured by asking about the number of members in the network, how often they had contacts with these members, and whether they had a close relationship. The differential association of loneliness and the components of the social network with health was assessed by means of hierarchical linear regression models, controlling for relevant covariates. In all three countries, loneliness was the variable most strongly correlated with health after controlling for depression, age, and other covariates. Loneliness contributed more strongly to health than any component of the social network. The relationship between loneliness and health was stronger in Finland (|β| = 0.25) than in Poland (|β| = 0.16) and Spain (|β| = 0.18). Frequency of contact was the only component of the social network that was moderately correlated with health. Loneliness has a stronger association with health than the components of the social network. This association is similar in three different European countries with different socio-economic and health characteristics and welfare systems. The importance of evaluating and screening feelings of loneliness in individuals with health problems should be taken into account. Further studies are needed in order to be able to confirm the associations found in the present study and infer causality.
Mellor-Marsá, B; Miret, M; Abad, FJ; Chatterji, S; Olaya, B; Tobiasz-Adamczyk, B; Koskinen, S; Leonardi, M; Haro, JM; Ayuso-Mateos, JL; Caballero, FF
Measurement Invariance of the Day Reconstruction Method: Results from the COURAGE in Europe Project Artículo de revista
En: Journal of Happiness Studies, vol. 17, no. 5, pp. 1769–1787, 2016, ISSN: 1573-7780.
Resumen | Enlaces | BibTeX | Etiquetas:
@article{Mellor-Mars\'{a}2016,
title = {Measurement Invariance of the Day Reconstruction Method: Results from the COURAGE in Europe Project},
author = {Mellor-Mars\'{a}, B and Miret, M and Abad, FJ and Chatterji, S and Olaya, B and Tobiasz-Adamczyk, B and Koskinen, S and Leonardi, M and Haro, JM and Ayuso-Mateos, JL and Caballero, FF},
url = {https://doi.org/10.1007/s10902-015-9669-x},
doi = {10.1007/s10902-015-9669-x},
issn = {1573-7780},
year = {2016},
date = {2016-01-01},
journal = {Journal of Happiness Studies},
volume = {17},
number = {5},
pages = {1769--1787},
abstract = {Given the growing interest in the study of subjective well-being as a measure of social progress, instruments that produce valid and reliable scores and that can be used within and across countries are needed. The aim of the present study was to analyze the measurement equivalence of the Day Reconstruction Method in its brief version, using nationally representative samples from Finland, Poland, and Spain obtained within the COURAGE in Europe project. The goodness-of-fit of a two-correlated-factors model and the reliability of the scores obtained were assessed. Cross-country invariance was tested employing a multiple group confirmatory factor analysis, through sequential constraint imposition. In each country, measurement invariance was tested across time frames (morning, afternoon and evening) and days of the week (weekday and weekend). The results found support for the hypothesis of a two-correlated-factors (positive and negative affect) structure; the reliability of the positive, the negative and the net affect scores showed appropriate values. A high equivalence across the three national samples was found: all items except one showed strong measurement invariance indicating that respondents from Finland, Poland, and Spain attribute the same meaning to the latent construct under study, and the levels of the underlying items are equal in all three countries. Similar results were found for the measurement equivalence across time frames and days of the week. Our findings support the assumption of comparability across the different samples considered; in general, higher positive affect and lower negative affect were found in Finland, in the evening and at the weekend.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Given the growing interest in the study of subjective well-being as a measure of social progress, instruments that produce valid and reliable scores and that can be used within and across countries are needed. The aim of the present study was to analyze the measurement equivalence of the Day Reconstruction Method in its brief version, using nationally representative samples from Finland, Poland, and Spain obtained within the COURAGE in Europe project. The goodness-of-fit of a two-correlated-factors model and the reliability of the scores obtained were assessed. Cross-country invariance was tested employing a multiple group confirmatory factor analysis, through sequential constraint imposition. In each country, measurement invariance was tested across time frames (morning, afternoon and evening) and days of the week (weekday and weekend). The results found support for the hypothesis of a two-correlated-factors (positive and negative affect) structure; the reliability of the positive, the negative and the net affect scores showed appropriate values. A high equivalence across the three national samples was found: all items except one showed strong measurement invariance indicating that respondents from Finland, Poland, and Spain attribute the same meaning to the latent construct under study, and the levels of the underlying items are equal in all three countries. Similar results were found for the measurement equivalence across time frames and days of the week. Our findings support the assumption of comparability across the different samples considered; in general, higher positive affect and lower negative affect were found in Finland, in the evening and at the weekend.
Kamenov, K; Caballero, F F; Miret, M; Leonardi, M; Sainio, P; Tobiasz-Adamczyk, B; Haro, J M; Chatterji, S; Ayuso-Mateos, J L; Cabello, M
Which Are the Most Burdensome Functioning Areas in Depression? A Cross-National Study Artículo de revista
En: Front Psychol, vol. 7, pp. 1342, 2016.
@article{pmid27630609,
title = {Which Are the Most Burdensome Functioning Areas in Depression? A Cross-National Study},
author = {K Kamenov and F F Caballero and M Miret and M Leonardi and P Sainio and B Tobiasz-Adamczyk and J M Haro and S Chatterji and J L Ayuso-Mateos and M Cabello},
year = {2016},
date = {2016-01-01},
journal = {Front Psychol},
volume = {7},
pages = {1342},
abstract = {The study aimed to identify the most burdensome functioning domains in depression and their differential impact on the quality of life (QoL) of individuals from nine countries in Asia, Africa, Europe, and Latin America. Data from two multi-country projects-the World Health Organization's Study on Global Ageing and Adult Health (SAGE) and the Collaborative Research on Ageing in Europe (COURAGE)-were analyzed. Eight functioning domains (pain, mobility, self-care, cognition, interpersonal activities, domestic life, and work, sleep and energy, and affect) and QoL were assessed in 4051 individuals with depression. The analyses of the pooled sample showed that affect (\ss = -0.21, p < 0.001), domestic life and work (\ss = -0.16, p < 0.001) and interpersonal activities (\ss = -0.15, p < 0.001) were the most affected functioning domains. When the analysis was stratified by gender, women showed similar patterns to the total sample, whereas mobility, self-care, cognition and pain were not significant amongst men. The cross-national analysis revealed that difficulties in affect and interpersonal activities were common across countries, whereas the rest of the domains showed country variability. In addition, being a woman (\ss = -0.05), being older (\ss = 0.07), being married (\ss = 0.05), not having a comorbid condition (\ss = -0.03) and having a higher education (\ss = 0.04) were all factors associated with higher levels of QoL. There was a variation in the level of decrements in different functioning domains across countries. This is in line with the growing evidence that reporting functioning sum-scores obscures potential differences among people. Functioning tools should capture the distinctiveness among individuals in order to provide tailored responses.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The study aimed to identify the most burdensome functioning domains in depression and their differential impact on the quality of life (QoL) of individuals from nine countries in Asia, Africa, Europe, and Latin America. Data from two multi-country projects-the World Health Organization's Study on Global Ageing and Adult Health (SAGE) and the Collaborative Research on Ageing in Europe (COURAGE)-were analyzed. Eight functioning domains (pain, mobility, self-care, cognition, interpersonal activities, domestic life, and work, sleep and energy, and affect) and QoL were assessed in 4051 individuals with depression. The analyses of the pooled sample showed that affect (ß = -0.21, p < 0.001), domestic life and work (ß = -0.16, p < 0.001) and interpersonal activities (ß = -0.15, p < 0.001) were the most affected functioning domains. When the analysis was stratified by gender, women showed similar patterns to the total sample, whereas mobility, self-care, cognition and pain were not significant amongst men. The cross-national analysis revealed that difficulties in affect and interpersonal activities were common across countries, whereas the rest of the domains showed country variability. In addition, being a woman (ß = -0.05), being older (ß = 0.07), being married (ß = 0.05), not having a comorbid condition (ß = -0.03) and having a higher education (ß = 0.04) were all factors associated with higher levels of QoL. There was a variation in the level of decrements in different functioning domains across countries. This is in line with the growing evidence that reporting functioning sum-scores obscures potential differences among people. Functioning tools should capture the distinctiveness among individuals in order to provide tailored responses.
Martin-Maria, N; Caballero, F F; Olaya, B; Rodriguez-Artalejo, F; Haro, J M; Miret, M; Ayuso-Mateos, J L
Positive Affect Is Inversely Associated with Mortality in Individuals without Đepression Artículo de revista
En: Front Psychol, vol. 7, pp. 1040, 2016.
@article{pmid27462289,
title = {Positive Affect Is Inversely Associated with Mortality in Individuals without {D}epression},
author = {N Martin-Maria and F F Caballero and B Olaya and F Rodriguez-Artalejo and J M Haro and M Miret and J L Ayuso-Mateos},
year = {2016},
date = {2016-01-01},
journal = {Front Psychol},
volume = {7},
pages = {1040},
abstract = {Some studies have analyzed the relation between well-being and mortality but none of them have attempted to disentangle the differential influence that positive affect, negative affect, and evaluative well-being might have on mortality using a longitudinal design in the general population and measuring independently and accurately each component of well-being. The aim of the present study is to assess the association of these well-being components with mortality after adjusting for health and other lifestyle factors and to analyze whether this association is different in people with and without depression. A nationally representative sample of 4753 people from Spain was followed up after 3 years. Analyses were performed with Cox regression models among the total sample and separately in people with and without depression. In the analyses adjusted for age, sex, and years of education, all three well-being variables showed separately a statistically significant association with mortality. However, after adjustment for health status and other confounders including the other well-being components, only positive affect remained as marginally associated with a decreased risk of mortality in the overall sample [HR = 0.87; 95% CI = 0.73-1.03], in particular among individuals without depression [HR = 0.82; 95% CI = 0.68-0.99]. Positive affect is inversely associated with mortality in individuals without depression. Future research should focus on assessing interventions associated with a higher level of positive affect.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Some studies have analyzed the relation between well-being and mortality but none of them have attempted to disentangle the differential influence that positive affect, negative affect, and evaluative well-being might have on mortality using a longitudinal design in the general population and measuring independently and accurately each component of well-being. The aim of the present study is to assess the association of these well-being components with mortality after adjusting for health and other lifestyle factors and to analyze whether this association is different in people with and without depression. A nationally representative sample of 4753 people from Spain was followed up after 3 years. Analyses were performed with Cox regression models among the total sample and separately in people with and without depression. In the analyses adjusted for age, sex, and years of education, all three well-being variables showed separately a statistically significant association with mortality. However, after adjustment for health status and other confounders including the other well-being components, only positive affect remained as marginally associated with a decreased risk of mortality in the overall sample [HR = 0.87; 95% CI = 0.73-1.03], in particular among individuals without depression [HR = 0.82; 95% CI = 0.68-0.99]. Positive affect is inversely associated with mortality in individuals without depression. Future research should focus on assessing interventions associated with a higher level of positive affect.
Coenen, M; Cabello, M; Umlauf, S; Ayuso-Mateos, J L; Anczewska, M; Tourunen, J; Leonardi, M; Cieza, A; Cieza, A; Coenen, M; Gall, H; Kollerits, B; Sabariego, C; Ayuso-Mateos, J L; Cabello, M; Mellor, B; Vigil, J; Leonardi, M; Cerniauskaite, M; Covelli, V; Giovannetti, A; Quintas, R; Raggi, A; Schiavolin, S; Chatterji, S; Bickenbach, J; Ballert, C; Brach, M; Luckenkemper, M; Baker, M; Benbow, A; Hawrot, T; Hartley, S; Psychiatrii, I; Anczewska, M; Charzy?ska, K; Chrostek, A; ?witaj, P; Roszczy?ska-Michta, J; Waszkiewicz, J; Finocchiaro, C; Cogoni, S; Pitkanen, T; Holopainen, A; Jokela, K; Kaskela, T; Levola, J; Tourunen, J
Psychosocial difficulties from the perspective of persons with neuropsychiatric disorders Artículo de revista
En: Disabil Rehabil, vol. 38, no. 12, pp. 1134–1145, 2016.
@article{pmid26289372b,
title = {Psychosocial difficulties from the perspective of persons with neuropsychiatric disorders},
author = {M Coenen and M Cabello and S Umlauf and J L Ayuso-Mateos and M Anczewska and J Tourunen and M Leonardi and A Cieza and A Cieza and M Coenen and H Gall and B Kollerits and C Sabariego and J L Ayuso-Mateos and M Cabello and B Mellor and J Vigil and M Leonardi and M Cerniauskaite and V Covelli and A Giovannetti and R Quintas and A Raggi and S Schiavolin and S Chatterji and J Bickenbach and C Ballert and M Brach and M Luckenkemper and M Baker and A Benbow and T Hawrot and S Hartley and I Psychiatrii and M Anczewska and K Charzy?ska and A Chrostek and P ?witaj and J Roszczy?ska-Michta and J Waszkiewicz and C Finocchiaro and S Cogoni and T Pitkanen and A Holopainen and K Jokela and T Kaskela and J Levola and J Tourunen},
year = {2016},
date = {2016-01-01},
journal = {Disabil Rehabil},
volume = {38},
number = {12},
pages = {1134--1145},
abstract = {The objective of this study is to determine whether persons with neuropsychiatric disorders experience a common set of psychosocial difficulties using qualitative data from focus groups and individual interviews. The study was performed in five European countries (Finland, Italy, Germany, Poland and Spain) using the focus groups and individual interviews with persons with nine neuropsychiatric disorders (dementia, depression, epilepsy, migraine, multiple sclerosis, Parkinson's disease, schizophrenia, stroke and substance dependence). Digitally recorded sessions were analysed using a step-by-step qualitative and quantitative methodology resulting in the compilation of a common set of psychosocial difficulties using the International Classification of Functioning, Disability and Health (ICF) as a framework. Sixty-seven persons participated in the study. Most persons with neuropsychiatric disorders experience difficulties in emotional functions, sleeping, carrying out daily routine, working and interpersonal relationships in common. Sixteen out of 33 psychosocial difficulties made up the common set. This set includes mental functions, pain and issues addressing activities and participation and provides first evidence for the hypothesis of horizontal epidemiology of psychosocial difficulties in neuropsychiatric disorders. This study provides information about psychosocial difficulties that should be covered in the treatment and rehabilitation of persons with neuropsychiatric disorders regardless of clinical diagnoses. Emotional problems, work and sleep problems should be addressed in all the treatments of neuropsychiatric disorders regardless of their specific diagnosis, etiology and severity. Personality issues should be targeted in the treatment for neurological disorders, whereas communication skill training may also be useful for mental disorders. The effects of medication and social environment on patient's daily life should be considered in all the neuropsychiatric conditions.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The objective of this study is to determine whether persons with neuropsychiatric disorders experience a common set of psychosocial difficulties using qualitative data from focus groups and individual interviews. The study was performed in five European countries (Finland, Italy, Germany, Poland and Spain) using the focus groups and individual interviews with persons with nine neuropsychiatric disorders (dementia, depression, epilepsy, migraine, multiple sclerosis, Parkinson's disease, schizophrenia, stroke and substance dependence). Digitally recorded sessions were analysed using a step-by-step qualitative and quantitative methodology resulting in the compilation of a common set of psychosocial difficulties using the International Classification of Functioning, Disability and Health (ICF) as a framework. Sixty-seven persons participated in the study. Most persons with neuropsychiatric disorders experience difficulties in emotional functions, sleeping, carrying out daily routine, working and interpersonal relationships in common. Sixteen out of 33 psychosocial difficulties made up the common set. This set includes mental functions, pain and issues addressing activities and participation and provides first evidence for the hypothesis of horizontal epidemiology of psychosocial difficulties in neuropsychiatric disorders. This study provides information about psychosocial difficulties that should be covered in the treatment and rehabilitation of persons with neuropsychiatric disorders regardless of clinical diagnoses. Emotional problems, work and sleep problems should be addressed in all the treatments of neuropsychiatric disorders regardless of their specific diagnosis, etiology and severity. Personality issues should be targeted in the treatment for neurological disorders, whereas communication skill training may also be useful for mental disorders. The effects of medication and social environment on patient's daily life should be considered in all the neuropsychiatric conditions.
Miret, M; López-García, P
Effect of Economic Crises on Suicide Rates Capítulo de libro
En: Courtet, Philippe (Ed.): pp. 191–198, Springer International Publishing, Cham, 2016, ISBN: 978-3-319-26282-6.
Resumen | Enlaces | BibTeX | Etiquetas:
@inbook{Miret2016,
title = {Effect of Economic Crises on Suicide Rates},
author = {Miret, M and L\'{o}pez-Garc\'{i}a, P},
editor = {Philippe Courtet},
url = {https://doi.org/10.1007/978-3-319-26282-6_15},
doi = {10.1007/978-3-319-26282-6_15},
isbn = {978-3-319-26282-6},
year = {2016},
date = {2016-01-01},
pages = {191--198},
publisher = {Springer International Publishing},
address = {Cham},
abstract = {Economic crises can cause adverse health effects, such as an increase in the prevalence of mental disorders and suicide rates. Nevertheless, these effects might vary across countries. While some countries successfully decouple economic crises from adverse mental health outcomes, in others the suicide rates increase due to economic crises. The differential impact of the economic crises on suicide may depend on some of the policies taken to tackle the financial downturn. Some of the mechanisms that underlay the association between suicide and economic crisis are increased unemployment, job insecurity, decreased earnings, personal debt and sudden bankruptcy. Several measures can be taken in order to prevent or decrease the negative effects of economic downturns on suicide, such as reducing the barriers to accessing health care, improving the quality of treatment of mental disorders with special attention to depression, raising the price of spirits, providing support to tackle financial problems, investing in labour market programmes and encouraging social support.},
keywords = {},
pubstate = {published},
tppubtype = {inbook}
}
Economic crises can cause adverse health effects, such as an increase in the prevalence of mental disorders and suicide rates. Nevertheless, these effects might vary across countries. While some countries successfully decouple economic crises from adverse mental health outcomes, in others the suicide rates increase due to economic crises. The differential impact of the economic crises on suicide may depend on some of the policies taken to tackle the financial downturn. Some of the mechanisms that underlay the association between suicide and economic crisis are increased unemployment, job insecurity, decreased earnings, personal debt and sudden bankruptcy. Several measures can be taken in order to prevent or decrease the negative effects of economic downturns on suicide, such as reducing the barriers to accessing health care, improving the quality of treatment of mental disorders with special attention to depression, raising the price of spirits, providing support to tackle financial problems, investing in labour market programmes and encouraging social support.
Prada, FA; Caridad Bocija Nogués, M; de La Osa Belloch, H; AM, Sanz Prada; Cabello, M; García Perez, J
Estado de salud en los adolescentes del Centro de Primera Acogida de Protección Hortaleza en la Comunidad de Madrid (2008-2012) Artículo de revista
En: Revista española de pediatría: clínica e investigación, vol. 72, no. 1, pp. 11–32, 2016.
BibTeX | Etiquetas:
@article{belver2016estado,
title = {Estado de salud en los adolescentes del Centro de Primera Acogida de Protecci\'{o}n Hortaleza en la Comunidad de Madrid (2008-2012)},
author = {Prada, FA and Caridad Bocija Nogu\'{e}s, M and de La Osa Belloch, H and Sanz Prada AM and Cabello, M and Garc\'{i}a Perez, J},
year = {2016},
date = {2016-01-01},
journal = {Revista espa\~{n}ola de pediatr\'{i}a: cl\'{i}nica e investigaci\'{o}n},
volume = {72},
number = {1},
pages = {11--32},
publisher = {Ergon},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Garcia-Esquinas, E; Perez-Hernandez, B; Guallar-Castillon, P; Banegas, J R; Ayuso-Mateos, J L; Rodriguez-Artalejo, F
Housing conditions and limitations in physical function among older adults Artículo de revista
En: J Epidemiol Community Health, vol. 70, no. 10, pp. 954–960, 2016.
@article{pmid27225681,
title = {Housing conditions and limitations in physical function among older adults},
author = {E Garcia-Esquinas and B Perez-Hernandez and P Guallar-Castillon and J R Banegas and J L Ayuso-Mateos and F Rodriguez-Artalejo},
year = {2016},
date = {2016-00-01},
journal = {J Epidemiol Community Health},
volume = {70},
number = {10},
pages = {954--960},
abstract = {Housing conditions are an important social determinant of health. However, to the best of our knowledge, no previous study has systematically assessed the association between housing conditions and physical function limitations in older adults; moreover, whether this association is independent of the socioeconomic status achieved earlier in life is still uncertain. Cross-sectional analysis conducted among 2012 non-institutionalised individuals aged \^{a}‰¥60 years, who participated in the Seniors-ENRICA cohort. Participants reported the following poor housing conditions: living in a walk-up building, lacking heating, or feeling cold frequently. We assessed lower extremity performance with the Short Physical Performance Battery (SPPB), mobility or agility limitations with standardised questions, frailty according to the Fried criteria, and disability in instrumental activities of daily living (IADL) with the Lawton and Brody questionnaire. In analyses adjusting for demographic, behavioural and comorbidity variables, when compared with those living in homes without poor housing conditions, those with \^{a}‰¥2 poor conditions showed worse scores in the SPPB (\^{I}² -1.06; 95% CI -1.46 to -0.65) and a higher frequency of agility limitation (OR 1.62; 95% CI 1.00 to 2.61) and frailty (OR 8.78; 95% CI 3.00 to 25.60). These associations held after adjustment for educational and occupational levels. Living in a walk-up building was associated with a higher frequency of frailty, while lacking heating was linked to lower scores in the 3 SPPB tests, as well as with an increased frequency of frailty and 4 of its components (exhaustion, slow walking speed, low physical activity and weakness). Feeling cold was linked to increased exhaustion. No association was found between housing conditions and IADL disability. Poor housing conditions, particularly living in a walk-up building and lacking heating, are independently associated with limitations in physical function in older adults. This entails serious inequalities in functional status, which should be firmly addressed.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Housing conditions are an important social determinant of health. However, to the best of our knowledge, no previous study has systematically assessed the association between housing conditions and physical function limitations in older adults; moreover, whether this association is independent of the socioeconomic status achieved earlier in life is still uncertain. Cross-sectional analysis conducted among 2012 non-institutionalised individuals aged ≥60 years, who participated in the Seniors-ENRICA cohort. Participants reported the following poor housing conditions: living in a walk-up building, lacking heating, or feeling cold frequently. We assessed lower extremity performance with the Short Physical Performance Battery (SPPB), mobility or agility limitations with standardised questions, frailty according to the Fried criteria, and disability in instrumental activities of daily living (IADL) with the Lawton and Brody questionnaire. In analyses adjusting for demographic, behavioural and comorbidity variables, when compared with those living in homes without poor housing conditions, those with ≥2 poor conditions showed worse scores in the SPPB (β -1.06; 95% CI -1.46 to -0.65) and a higher frequency of agility limitation (OR 1.62; 95% CI 1.00 to 2.61) and frailty (OR 8.78; 95% CI 3.00 to 25.60). These associations held after adjustment for educational and occupational levels. Living in a walk-up building was associated with a higher frequency of frailty, while lacking heating was linked to lower scores in the 3 SPPB tests, as well as with an increased frequency of frailty and 4 of its components (exhaustion, slow walking speed, low physical activity and weakness). Feeling cold was linked to increased exhaustion. No association was found between housing conditions and IADL disability. Poor housing conditions, particularly living in a walk-up building and lacking heating, are independently associated with limitations in physical function in older adults. This entails serious inequalities in functional status, which should be firmly addressed.
0000
José Luis Ayuso-Mateos,; Daniel Morillo,; Josep Maria Haro,; Beatriz Olaya,; Elvira Lara,; Miret., Marta
Changes on depression and suicidal ideation under severe lockdown restrictions during the first wave of the COVID-19 pandemic in Spain: a longitudinal study in the general population. Artículo de revista
En: Epidemiology and Psychiatric Sciences., 0000.
BibTeX | Etiquetas:
@article{Ayuso-Mateos2021,
title = {Changes on depression and suicidal ideation under severe lockdown restrictions during the first wave of the COVID-19 pandemic in Spain: a longitudinal study in the general population.},
author = {Jos\'{e} Luis Ayuso-Mateos, and Daniel Morillo, and Josep Maria Haro, and Beatriz Olaya, and Elvira Lara, and Marta Miret.},
journal = {Epidemiology and Psychiatric Sciences.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Jesus Pastor,; Vega-Zelaya, Lorena; Parada, Eduardo Delgado; Mateos, Jose L Ayuso
Electroencephalographic evidence of organic alteration in a patient with SARS-CoV2 induced delirium Acta de congreso
0000, ISSN: 2631-5416.
BibTeX | Etiquetas:
@proceedings{Pastor2021,
title = {Electroencephalographic evidence of organic alteration in a patient with SARS-CoV2 induced delirium},
author = {Jesus Pastor, and Lorena Vega-Zelaya and Eduardo Delgado Parada and Jose L Ayuso Mateos},
issn = {2631-5416},
journal = {Clinical Case Studies and Reports},
keywords = {},
pubstate = {published},
tppubtype = {proceedings}
}
Mediavilla, Roberto; Muñoz-Sanjose, Ainoa; Rodriguez-Vega, Beatriz; Lahera, Guillermo; Palao, Angela; Bayon, Carmen; Vidal-Villegas, Maria-Paz; Chadwick, Paul; Bravo-Ortiz, Maria-Fe
People with psychosis improve affective social cognition and self-care after a mindfulness-based social cognition training program (SocialMIND) Artículo de revista
En: Psychiatric Rehabilitation Journal, 0000.
BibTeX | Etiquetas:
@article{Mediavilla2021,
title = {People with psychosis improve affective social cognition and self-care after a mindfulness-based social cognition training program (SocialMIND)},
author = {Mediavilla, Roberto and Mu\~{n}oz-Sanjose, Ainoa and Rodriguez-Vega, Beatriz and Lahera, Guillermo and Palao, Angela and Bayon, Carmen and Vidal-Villegas, Maria-Paz and Chadwick, Paul and Bravo-Ortiz, Maria-Fe},
journal = {Psychiatric Rehabilitation Journal},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Mediavilla, Roberto; Muñoz-Sanjose, Ainoa; Rodriguez-Vega, Beatriz; Lahera, Guillermo; Palao, Angela; Bayon, Carmen; Vidal-Villegas, Maria-Paz; Chadwick, Paul; Bravo-Ortiz, Maria-Fe
People with psychosis improve affective social cognition and self-care after a mindfulness-based social cognition training program (SocialMIND) Artículo de revista
En: Psychiatric Rehabilitation Journal, 0000.
BibTeX | Etiquetas:
@article{Mediavilla2021b,
title = {People with psychosis improve affective social cognition and self-care after a mindfulness-based social cognition training program (SocialMIND)},
author = {Mediavilla, Roberto and Mu\~{n}oz-Sanjose, Ainoa and Rodriguez-Vega, Beatriz and Lahera, Guillermo and Palao, Angela and Bayon, Carmen and Vidal-Villegas, Maria-Paz and Chadwick, Paul and Bravo-Ortiz, Maria-Fe},
journal = {Psychiatric Rehabilitation Journal},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
E.and Manzano-García Ruiz-Parra, G. and Mediavilla; Rodríguez-Vega, B.; Lahera, G.; Moreno-Pérez, A. I.; Torres-Cantero, A. M.; Rodado-Martínez, J.; A. Bilbao, & González-Torres
The Spanish version of the reflective functioning questionnaire: Validity data in the general population and individuals with personality disorders Artículo de revista
En: PLOS ONE, vol. 18, no. 4, 0000.
@article{Ruiz-Parra2023,
title = {The Spanish version of the reflective functioning questionnaire: Validity data in the general population and individuals with personality disorders},
author = {Ruiz-Parra, E.and Manzano-Garc\'{i}a, G.and Mediavilla, R. and Rodr\'{i}guez-Vega, B. and Lahera, G. and Moreno-P\'{e}rez, A. I. and Torres-Cantero, A. M. and Rodado-Mart\'{i}nez, J. and Bilbao, A., \& Gonz\'{a}lez-Torres, M. \'{A}.},
url = {https://doi.org/10.1371/journal.pone.0274378},
doi = {10.1371/journal.pone.0274378},
journal = {PLOS ONE},
volume = {18},
number = {4},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Purgato, M.; Turrini, G.; Tedeschi, F.; Serra, R.; Tarsitani, L.; Compri, B.; Muriago, G.; Cadorin, C.; Ostuzzi, G.; Nicaise, P.; Lorant, V.; Sijbrandij, M.; Witteveen, A. B.; Ayuso-Mateos, J. L.; Mediavilla, R.; Haro, J. M.; Felez-Nobrega, M.; Figueiredo, N.; Pollice, G.; Barbui, C.
Effectiveness of a stepped-care programme of WHO psychological interventions in migrant populations resettled in Italy: Study protocol for the RESPOND randomized controlled trial. Artículo de revista En preparación
En: Frontiers in Public Health,, vol. 11, En preparación.
@article{Purgato2023,
title = {Effectiveness of a stepped-care programme of WHO psychological interventions in migrant populations resettled in Italy: Study protocol for the RESPOND randomized controlled trial.},
author = {Purgato, M. and Turrini, G. and Tedeschi, F. and Serra, R. and Tarsitani, L. and Compri, B. and Muriago, G. and Cadorin, C. and Ostuzzi, G. and Nicaise, P. and Lorant, V. and Sijbrandij, M. and Witteveen, A. B. and Ayuso-Mateos, J. L. and Mediavilla, R. and Haro, J. M. and Felez-Nobrega, M. and Figueiredo, N. and Pollice, G. and Barbui, C.},
url = {https://www.frontiersin.org/articles/10.3389/fpubh.2023.1100546},
doi = {10.3389/fpubh.2023.1100546},
journal = {Frontiers in Public Health,},
volume = {11},
keywords = {},
pubstate = {forthcoming},
tppubtype = {article}
}